Efficient offloading and load distribution based on D2D relaying and UAVs for emergent wireless networks

The device to device (D2D) and unmanned aerial vehicle (UAV) communications are considered as enabling technologies of the emergent 5th generation of wireless and cellular system (5G). Consequently, it is important to determine their corresponding performance with respect to the 5G requirements. In particular, we focus on enhancing the offloading and load balancing performance in three directions. In the first direction, we study the achievable data rate of user relay assisting other users in two-tier networks. We propose a novel heuristic communication scheme called device-for-device (D4D). The D4D enables moving users to share their resource by taking advantage of cooperative communication. We study the moving user rate sensitivity to the relay selection and blocking probability. In the second direction, we study the offloading from macrocell to small cell and load balancing among small cell. Also, we design a new utility weight function that enables a balanced relay assignment. We propose a novel low complexity algorithm for centralized scheme maximizing the load among small cells as well as users subject to SINR threshold constraints. The simulations show that our proposed schemes achieve performance in load balancing compared to those obtained with the previous or traditional method. In the third direction, we study the 3D deployment of multiple UAVs for emergent on-demand offloading. We propose a novel on-demand deployment scheme based on maximizing both the operator’s profit and the quality of service. The proposed scheme is based on solving a non-convex problem by combining k-means clustering with pattern search to find the suboptimal location of UAVs. The simulation results show that our proposed scheme maximizes the operator’s profit and improves offloading traffic efficiency. Our global contribution was the development of a scheme to improve the quality of service and the performance in emergent networks through the improvement of the load distribution and resource sharing using D2D and UAV

Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study

OBJECTIVES: Paediatric cancer is a leading cause of death for children. Children in low-income and middle-income countries (LMICs) were four times more likely to die than children in high-income countries (HICs). This study aimed to test the hypothesis that the COVID-19 pandemic had affected the delivery of healthcare services worldwide, and exacerbated the disparity in paediatric cancer outcomes between LMICs and HICs. DESIGN: A multicentre, international, collaborative cohort study. SETTING: 91 hospitals and cancer centres in 39 countries providing cancer treatment to paediatric patients between March and December 2020. PARTICIPANTS: Patients were included if they were under the age of 18 years, and newly diagnosed with or undergoing active cancer treatment for Acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, Wilms' tumour, sarcoma, retinoblastoma, gliomas, medulloblastomas or neuroblastomas, in keeping with the WHO Global Initiative for Childhood Cancer. MAIN OUTCOME MEASURE: All-cause mortality at 30 days and 90 days. RESULTS: 1660 patients were recruited. 219 children had changes to their treatment due to the pandemic. Patients in LMICs were primarily affected (n=182/219, 83.1%). Relative to patients with paediatric cancer in HICs, patients with paediatric cancer in LMICs had 12.1 (95% CI 2.93 to 50.3) and 7.9 (95% CI 3.2 to 19.7) times the odds of death at 30 days and 90 days, respectively, after presentation during the COVID-19 pandemic (p<0.001). After adjusting for confounders, patients with paediatric cancer in LMICs had 15.6 (95% CI 3.7 to 65.8) times the odds of death at 30 days (p<0.001). CONCLUSIONS: The COVID-19 pandemic has affected paediatric oncology service provision. It has disproportionately affected patients in LMICs, highlighting and compounding existing disparities in healthcare systems globally that need addressing urgently. However, many patients with paediatric cancer continued to receive their normal standard of care. This speaks to the adaptability and resilience of healthcare systems and healthcare workers globally